Preeclampsia is a multifactorial disease during pregnancy. Dysregulated lipid metabolism may be related to some preeclampsia. We investigated the relationship between triglycerides (TGs) and liver injury in different preeclampsia-like mouse models and their potential common pathways.
que es preeclampsia pdf download
Earlier preeclampsia onset causes a higher MAP and urine protein level, and more severe placental and fetal damage. Preeclampsia-like models generated by varied means lead to different changes in lipid metabolism and associated with liver injury. Trophoblastic mitochondrial damage may be the common terminal pathway in different preeclampsia-like models.
At the general hospital she was diagnosed as having severe preeclampsia and she was managed with magnesium sulfate and an antihypertensive medication for 2 days. She was counseled to have induction of labor by the attending physician but refused to give consent and went home. She returned to the referral hospital 2 days later after labor had started spontaneously at home and the delivery was a spontaneous vaginal delivery with outcome of a live male baby, his Apgar score was 6/10 immediately after birth and he weighed 1.9 kg.
Because of shortage of supply and instruments, except urine analysis (protein 3+), no other laboratory or other investigative tests were done at the health center. The health care providers at the primary health facility diagnosed her as having preeclampsia and referred her to the nearby general hospital with an ambulance.
In the community, women who have had no obstetric problems during their previous pregnancies perceived that they will have no problems with their consecutive pregnancies and therefore feel that ANC and facility delivery was not useful. It was only necessary when severe complications occured that they attend health facilities. Moreover, women do not like to visit health facilities due to fear of pregnancy-related interventions like induction and instrumentation during delivery. Seizures due to eclampsia were perceived by the community as being caused by an evil spirit, and they prefer to take a preeclamptic/eclamptic mother to religious institutions rather than to health facilities. Women with preeclampsia/eclampsia may have underweight babies and visiting health facilities will be lifesaving for both the mother and her child.
Studies reported that not attending ANC, preeclampsia, multiple pregnancies, and bad obstetric history are significant maternal factors resulting in low birth weight babies and low birth weight babies are at a greater risk of having a disability and for diseases [17,18,19].
Factor V Leiden polymorphism is a well-recognized genetic factor in the etiology of preeclampsia. Considering that Ghana is recording high incidence of preeclampsia, we examined if factor V Leiden is a contributory factor to its development and pregnancy outcomes. 2ff7e9595c
Коментарі